Synake
PROLOU the secret ingredient - Synake
SYN®-AKE is a new anti-wrinkle active compound based on a synthetic tripeptide that mimics the effect of
waglerin 1, a peptide that is found in the venom of the Temple
Viper.
The Most revolutionary anti wrinkle cream on the market
today
Synake is an excellent anti-wrinkle active compound with
a snake venom-like mode of activity
Synake smoothes mimic wrinkles in a short period.
Synake age killing effect particularly effective against
expression lines

Synake is an intensive anti-wrinkles care.
Efficacy Tests
in vitro tests:
The efficacy of the Synake tripeptide (at a concentration
of 0.5mM) has been demonstrated in vitro by measuring the
frequency of contraction of the innervated muscle cell as
a function of the incubation time.
Synake peptide reduces muscle cell contraction and its action
if reversible.
In vivi tests:
The measurement of the smoothing and anti-wrinkle effect of
Synake (4%) was compared to a placebo. A cream was applied
to the forehead twice daily during 28 days.
Synake - Age Killing Effect.
The smoothing effect (Ra) was measured on 80% of the volunteers
and the anti-wrinkle effect (Rz, Rt) measured on 73% of the
volunteers.
Results showed up to 52% of wrinkle size after 28 days application!
Synake is a new anti-wrinkle active compound
based on a synthetic tripeptide that mimics the effect of
waglerin 1, a peptide that is found in the venom of the Temple
Viper, Tropidolaemus waglerin.
The Real "Age-Killing-Effect"
Synake: synthetic substance mimics snake venom activity
Snake venom can be deadly - but similar substances can also
heal!! The form. Of a "wrinkle-killer" it is being
used to help boost the self-confidence of both men and women.
Synake is a synthetic substance, which mimics part of a polypeptide
found in the venom of the Temple Viper. It has beneficial
effects for the skin - perhaps "Love at first bite”.
Lines caused by facial expressions are always visible. We
use about 60 facial muscles whilst communicating both through
speech and with facial expressions, frowning, the lifting
of eyebrows laughing and pulling a face are some typical facial
expressions that we use to communicate. As time passes and
with frequent use of these facial movements, these wrinkles
persist and become permanent deep wrinkles on the forehead,
laughter lines and crow's feet. Those who no longer want to
live with these can now spare themselves the danger and discomfort
of cosmetic surgery or the use of expensive injections.
Synake solves this problem on a strictly
cosmetic basis. The new synthetic Tripeptide mimics the effect
of Waglerin-1. Which is a protein found in the venom of the
Temple Viper (Tropidolaemus wagleri).
The viper owes its name
to the German herpe- tologist Johann Georg Wagler. At the
beginning of the 19th century, he analysed and described it.
The Temple~ Viper is found in great numbers in the Snake Temple
of the island Penang, Malaysia. It has enjoyed cult status
there for the last 150 years.
Waglerin-1 Inhibits neuromuscular
communication. Once the snake has bitten its prey the venom
blocks the nerve impulses to the muscles, thereby paralysing
its victim. Whereas this causes death, the synthetic imitation
of parts of the venom only causes relaxation of facial muscle
contractions, resulting in a smooth skin and a renewed enjoyment
of life.
The effectiveness of this substance is astounding: it has
excellent skin- smoothing properties and reduces the depth
of facial wrinkles in just a few days. A study involving 45
volunteers confirmed these results. During this test, the
use of Synake twice daily-reduced forehead wrinkles, by up
to 52% in just 28 days.
The in vivo studies dealing with crow's
feet confirmed the efficiency of the product. In vitro studies
show that Synake, in a concentration of 0.5 mm, reduces the
frequency of muscle contractions in innervated muscle cells
by 82% (p<O.05) within only 2 hours.
The active compound Synake is the result of Peptides synthesis
and expertise in snake venom research. The researchers at
Pentapharm have managed to make a remarkable transference
from the effects of snake venom peptides, which consist of
22 amino acids to a peptide-like com- pound containing only
3 amino acids.
This kind of research has long been a tradition
at Pentapharm. For 30 years, snake venom has been used for
therapeutic and diagnostic purposes. One example is the utilization
of the anti-coagulant properties of parts of the South American
Lance Adder venom. To this purpose, Pentapharm in Brazil maintains
a snake farm, housing and breeding about 10,000 snakes.
The venom is milked locally in Brazil. Then transported to
Switzerland for purification and further processing.
The synthetic peptide Synake thus enables Pentapharm to
dispense with the use of the snake farm. Synake is safe.
Indisputably, ecology-friendly and totally without risk, during
production (in line with our "Responsible Care Program").
It contains no preservative and is considered absolutely safe
for use in cosmetic products.


Official Retail Price - 44.00 € / £34.50 / $59.00
50 ml Jar |
Discount |
€ |
£ |
$ |
|
3 jars  |
-50% |
66.00 |
51.75 |
88.50 |
|
2 Jars |
-35% |
57.20 |
44.85 |
76.70 |
|
1 Jar |
-25% |
33.00 |
25.87 |
44.25 |
|
Your credit card will be debited in Euros. Sterling and Dollar prices are a guide only
Register Mail Shipping Costs
1 x Prolou Jar - European Union - 5.00 €
2 x Prolou Jar - European Union - 8.00 €
3 x Prolou Jar - European Union - 10.00 €
1 x Prolou Jar - Rest of World - 8.00 €
2 x Prolou Jar - Rest of World - 12.00 €
3 x Prolou Jar - Rest of World - 15.00 €
|